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Supportive Secondary End Points Relative to the placebo group, participants in the semaglutide group were more likely to have lost 20% or more of baseline body weight by week 68 (Table 2 and eTable 1 in Supplement 1)
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Intrathecal administration of GLP-1R agonists such as GLP-1(7–36) and exenatide alleviated hypersensitivity in models of formalin-induced, peripheral nerve injury-induced, bone cancer-induced, and diabetes-induced pain in mice and rats [31]
